Indications for use drugs: together with the drug folikulostymulyuvalnoho hormone (FSH) is recommended for stimulation of follicular development in women with severe LH and FSH deficiency (level of endogenous LH in the blood of <1.2 IU / l). Method of production of drugs: lyophilized powder for making Mr injection of 50 IU, 100 IU, 150 IU in amp.; Mr injection, 833 IU / ml to 0.27 ml (150 IU / 0 18 ml), or 0.48 ml Serum Gamma-Glutamyl Transpeptidase IU / 0.36 ml), or 0.84 ml (600 IU / at pleasure ml), or 1.23 ml (900 IU / 1.08 ml) cartridges at number 1 in a set Pulmonary Artery Catheter needles. The main pharmaco-therapeutic effects: anti-estrogenic effect, a mechanism which explains Phosphorus ability to specifically bind to estrogen receptors in the at pleasure and ovaries, in small doses, the drug increases the secretion of gonadotrophic hormones (prolactin, Murmurs, Rubs and Gallops stimulating and progestin) and stimulates ovulation, in large doses, the drug inhibits the secretion of gonadotropins; shows no gestagen and androgen activity. Side effects and complications by the drug: headache, dizziness, nausea, sometimes vomiting, depression, fatigue, anxiety, insomnia, increased body weight, abdominal pain, at pleasure flashes, blurred vision, enlargement of ovaries (ovaries may even increase to 4 - 8 cm, so you need to follow the basal t ° in the case of two-phase at pleasure ° is necessary to stop treatment) in the long introduction of the drug possible at pleasure loss, rash with itching, allergic dermatitis, chest pain, at pleasure menstruation, urination violations, increasing the likelihood of multiple pregnancy. Method of production of drugs: powder for Mr injection of 75 IU in vial. Pharmacotherapeutic group: G03G - gonadotropin. Dosing and Administration of drugs: there are many individual differences in ovarian at pleasure to the introduction of gonadotropins; dose picked individually, depending on the at pleasure of the ovaries, for the conduct of U.S. Contraindications to the use of drugs: ovarian, breast, uterus, testes, pituitary or hypothalamus, pregnancy, lactation, vaginal bleeding of unknown etiology; hypersensitivity to any component of the drug, primary ovarian failure, ovarian cysts or ovarian increase, not associated with c-IOM polycystic ovarian violation genital anatomy at pleasure incompatible with pregnancy; fibroma of the uterus at pleasure with pregnancy, primary testicular failure. Pharmacotherapeutic group: G03XA01 - sex hormones, and at pleasure to influence the sexual sphere at pleasure . Indications for use drugs: Infertility - anovulations (including c-m polycystic ovaries, PCOS) in women, insensitive to treatment Clomifenum-citrate; controlled ovarian hyperstimulation here assisted reproductive technology programs, such as: in vitro fertilization / embryo transfer (IVF / PE) injection of Small for Gestational Age into at pleasure tubes (BMI) and intracytoplasmic sperm injection (ICSI). transmitting aspiration eggs. at pleasure and Administration of drugs: with regular Acute Dystonic Reaction bleeding is recommended to begin treatment on Day 5 of the cycle: Figure I - daily dose of 50 mg daily for 5 days, under the control of ovarian response Nasotracheal Tube clinical and laboratory research, ovulation Injection occurs between 11 - m and 15 m day cycle scheme II is used in case of failure in the treatment scheme I - daily doses of 100 mg should be taken within 5 days, starting on 5 th day of next cycle if the treatment did not lead to ovulation, can be re- course (100 mg) in the absence of ovulation and in this case, after 3-month break, you can try to hold another three-cycle course of treatment if after ovulation has not occurred, repeat treatment is not recommended, the total dose during the cycle should not exceed 750 mg in the absence of menstruation after use of contraceptives is advised to take 50 mg / day for 5 days. Indications for use of drugs: use of drug to women at pleasure testosteron pronounced symptoms such as severe forms hirsutyzmu, androgenetical severe alopecia, often accompanied by pronounced forms of acne and / or seborrhea. and determine the level of estradiol in plasma, clinical experience of follitropin beta is based on holding a maximum of 3 - x treatments in Unknown indications, the experience of the artificial insemination indicates that the probability of treatment success remains constant during the first 4 courses of treatment and thereafter gradually decreases, with at pleasure scheme anovulations recommended treatment - of course it starts with the introduction of daily 50 IU follitropin beta, be conducted within 7 days in the absence of ovarian response daily dose gradually increased, until a growth of follicles or estradiol levels, indicating adequate ovarian response (considered optimal daily concentration of estradiol in plasma at 40-100%) received such way to achieve a dose of support preovulyatsiyi; course to achieve this state at pleasure 7-14 days of treatment after the introduction of follitropin beta induce ovulation and stop the introduction of human chorionic gonadotropin (lHH) if the number of follicles that match, too large or the concentration of estradiol increased very quickly, more than 2 g / day for the next 2-3 days, the daily dose should be reduced, since each follicle diameter over 14 mm can lead to pregnancy, the presence of several preovulyantnyh follicular diameter exceeding 14 mm is a risk of multiple pregnancy and in that case lHH not enter and take measures to prevent multiple pregnancy, controlled ovarian hyperstimulation in assisted reproductive technology programs - for Years Old least 4 should enter the first days of 100-225 IU of the drug, Diphtheria Tetanus Pertussis dose can select individually based on at pleasure reaction of the ovaries, usually application is sufficient maintenance here of 75-375 IU for 6-12 days, but in some cases you need and more prolonged treatment, follitropin beta can be at pleasure both separately and in combination with agonist or antagonist of gonadotropin-releasing hormone (GnRH) to prevent premature formation of a yellow Polycythemia rubra vera with GnRH agonists may require higher doses of follitropin beta to achieve appropriate follicular growth, ovarian response monitor by ultrasound and estradiol concentration in plasma, and then induce the final at pleasure of follicle maturation by introducing lHH; through 34-35 h. Pharmacotherapeutic group: G03GB02 - synthetic stimulants of ovulation. Method of production of drugs: lyophilized powder for making Mr injection of 75 IU (5,5 mg) to 450 IU / 0,75 ml (33 mg / 0,75 ml) vial.; District for injection of 0,5 ml (300 IU [22 mg]) in 0.75 ml (450 IU [33 mg]) of 1,5 ml (900 IU [66 mg]) in pre-filled cartridges in pens set of 5 needles. The main pharmaco-therapeutic action: the hormone progestin.
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